Tofacitinib(CP-690550)是高效JAK3抑制剂，IC50为1 nM，比对JAK2和JAK1的抑制性高20倍和100倍。
| Cas No. | 1092578-48-7 |
| 别名 | (3S,4R)-托法替尼 |
| Canonical SMILES | CN(C1=NC=NC2=C1C=CN2)[C@H]3[C@H](C)CCN(C(CC#N)=O)C3 |
| 分子式 | C16H20N6O |
| 分子量 | 312.37 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | (3S,4R)-Tofacitinib is an enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM. |
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