CAS NO: | 21178-57-4 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
Cas No. | 21178-57-4 |
别名 | α,β-dehydro Curvularin |
化学名 | (4S,8E)-4,5,6,7-tetrahydro-11,13-dihydroxy-4-methyl-2H-3-benzoxacyclododecin-2,10(1H)-dione |
Canonical SMILES | O=C1CC2=C(C(/C=C/CCC[C@H](C)O1)=O)C(O)=CC(O)=C2 |
分子式 | C16H18O5 |
分子量 | 290.3 |
溶解度 | 30mg/mL in DMSO, 30mg/mL in DMF, 10mg/mL in Ethanol |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 10,11-Dehydrocurvularin is an antibiotic and a strong activator of the heat shock response, a conserved evolutionary mechanism that maintains protein homeostasis via the overexpression of heat shock factor 1 (HSF1) and various chaperones including heat shock protein 90 (Hsp90). 10,11-Dehydrocurvularin inhibits TGF-β signalling pathway. Anti-tumorous activity[1][2]. References: |