CAS NO: | 916603-07-1 |
包装 | 价格(元) |
10mM (in 1mL DMSO) | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
Cas No. | 916603-07-1 |
别名 | N2-(4-(氨甲基)苯)-5-氟-N4-苯基嘧啶-2,4-二胺,CZC-00008004 |
Canonical SMILES | FC1=CN=C(NC2=CC=C(CN)C=C2)N=C1NC3=CC=CC=C3 |
分子式 | C17H16FN5 |
分子量 | 309.34 |
溶解度 | DMSO : 77.5 mg/mL (250.53 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | CZC-8004 is a pan-kinase inhibitor and binds a range of tyrosine kinases, including ABL kinase. [1]. CZC-8004 is a pan-kinase inhibitor, with low micromolar IC50 values for tyrosine kinase. [2]. Bantscheff M, et al. Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors. Nat Biotechnol. 2007 Sep;25(9):1035-44. |