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tcY-NH2 TFA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
tcY-NH2 TFA图片
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
tcY-NH2TFA是选择性的大鼠的PAR4肽类拮抗剂。tcY-NH2TFA抑制凝血酶和AY-NH2诱导的大鼠血小板聚集。
别名(trans-Cinnamoyl)-YPGKF-NH2 TFA
分子式C42H50F3N7O9
分子量853.88
溶解度DMSO: 250 mg/mL (292.78 mM)
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

tcY-NH2 TFA is a selective rat PAR4 antagonist peptide. tcY-NH2 TFA inhibits thrombin- and AY-NH2-induced rat platelet aggregation[1][2].

[1]. Morley D Hollenberg, et al. Proteinase-activated receptor-4: evaluation of tethered ligand-derived peptides as probes for receptor function and as inflammatory agonists in vivo. Br J Pharmacol. 2004 Oct;143(4):443-54. [2]. L Ma, et al. Thrombin-induced platelet endostatin release is blocked by a proteinase activated receptor-4 (PAR4) antagonist. Br J Pharmacol. 2001 Oct;134(4):701-4.