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GB-110
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GB-110图片
CAS NO:1252806-70-4
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
GB-110 是一种有效的,具有口服活性的,非肽类的 protease activated receptor 2 (PAR2) 激动剂,选择性诱导 PAR2 介导的 HT29 细胞内 Ca2+ 释放,EC50 值为 0.28 μM。
Cas No.1252806-70-4
Canonical SMILESO=C(C1=CC=NO1)N[C@@H](CC2CCCCC2)C(N[C@@H]([C@@H](C)CC)C(NCC3=CC=CC(C(N4CCC(CN)CC4)=O)=C3)=O)=O
分子式C33H48N6O5
分子量608.77
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

GB-110 is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. GB-110 selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM[1]. Protease activated receptor 2[1]

[1]. Barry GD, et al. Novel agonists and antagonists for human protease activated receptor 2. J Med Chem. 2010 Oct 28;53(20):7428-40.