您好，欢迎来到化工原料网！ [登录] [免费注册]
化工原料网
发布求购
位置：首页 > 产品库 > (±)10(11)-EpDPA
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
(±)10(11)-EpDPA
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
(±)10(11)-EpDPA图片
CAS NO:895127-65-8
包装与价格：
包装价格(元)
25μg电议
50μg电议
100μg电议
500μg电议

产品介绍
Cas No.895127-65-8
Canonical SMILESCC/C=C\C/C=C\C/C=C\C[C@@H](O1)[C@@H]1C/C=C\C/C=C\CCC(O)=O
分子式C22H32O3
分子量344.5
溶解度DMF: 25 mg/mL,DMSO: 20 mg/mL,Ethanol: 50 mg/mL,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)10(11)-EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 10,11-double bond of DHA. It has been detected in rat brain and spinal cord, as well as human serum, and acts as a substrate for soluble epoxide hydrolase with a Km value of 5.1 µM. (±)10(11)-EpDPA and other epoxy metabolites of DHA are reported to demonstrate antihyperalgesic activity in inflammatory and neuropathic pain models and to potently inhibit angiogenesis and tumor growth in in vitro assays.