Spirolaxine 是一种植物生长抑制剂,具有显着的抗幽门螺杆菌活性。
Cas No. | 126382-01-2 |
Canonical SMILES | OC1=CC(OC)=C(C(O[C@@H]2CCCCC[C@@H]3CCC[C@]4(CC[C@@H](C)O4)O3)=O)C2=C1 |
分子式 | C23H32O6 |
分子量 | 404.5 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Spirolaxine is a long-chain phthalide produced by the fungus S. laxum that has antibacterial properties. Spirolaxine is a potent anti-H. pylori agent (MIC = 0.2 µg/cm3) with weak activity against E. coli. Spirolaxine (1-40 µM) inhibits proliferation of endothelial (BMEC, HUVEC) and tumor (LoVo, HL-60) cells in culture. B. megaterium and C. echinulate produce hydroxylated metabolites of spirolaxine when given spirolaxine as a substrate. |