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TA 02
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
TA 02图片
CAS NO:1784751-19-4
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
10mg电议
50mg电议

产品介绍
TA 02 是 SB 203580 的类似物，是一种 p38 MAPK 抑制剂，IC50 为 20 nM。
Cas No.1784751-19-4
化学名4-(2-(2-fluorophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)pyridine
Canonical SMILESFC1=C(C2=NC(C3=CC=C(F)C=C3)=C(C4=CC=NC=C4)N2)C=CC=C1
分子式C20H13F2N3
分子量333.33
溶解度≥ 12.65mg/mL in DMSO
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.IC50 value: 20 nMTarget: p38TA-02 is a novel compound with similar cardiogenic properties asSB203580 and SB202190. TA-02 especially inhibits TGFBR-2.

References:
[1]. Laco F, et al. Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling. J Mol Cell Cardiol. 2015 Mar;80:56-70.
[2]. Filip LACO, et al. 2,4,5-tri-substituted azole-based casein kinase 1 inhibitors as inducers for cardiomyogenesis. WO 2015119579 A1.