包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
Canonical SMILES | O=C(OC1=C2C=CC(OCC(NO)=O)=C1Br)C3=C2CCCC3 |
分子式 | C15H14BrNO5 |
分子量 | 368.2 |
溶解度 | DMF: 10 mg/ml,DMSO: 10 mg/ml |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 8Br-HA is an inhibitor of fragile histidine triad diadenosine triphosphatase (FHIT; IC50= 0.12 µM).1It inhibits the growth of HCC827 and H460 lung cancer cells (GI50s = 0.87 and 5.9 µM, respectively). 1.Kawaguchi, M., Sekimoto, E., Ohta, Y., et al.Synthesis of fluorescent probes targeting tumor-suppressor protein FHIT and Identification of apoptosis-inducing FHIT inhibitorsJ. Med. Chem.64(13)9567-9576(2021) |