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2-deoxy-2-fluoro-D-Glucose
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
2-deoxy-2-fluoro-D-Glucose图片
CAS NO:29702-43-0
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
100mg电议

产品介绍
A glucose derivative with anticancer activity
Cas No.29702-43-0
别名2-脱氧-2-氟-D-葡萄糖
Canonical SMILESOC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](F)C=O
分子式C6H11FO5
分子量182.1
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2-deoxy-2-fluoro-D-Glucose (2-FG) is a derivative of glucose with anticancer activity.1It inhibits the growth of 143B osteosarcoma cells grown under normoxic and hypoxic conditions when used at concentrations of 6 and 24 mM.

1.Lampidis, T.J., Kurtoglu, M., Maher, J.C., et al.Efficacy of 2-halogen substituted ?-glucose analogs in blocking glycolysis and killing ''hypoxic tumor cells''Cancer Chemother. Pharmacol.58(6)725-734(2006)