| CAS NO: | 12626-17-4 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| Cas No. | 12626-17-4 |
| 别名 | 烟曲霉毒素B |
| Canonical SMILES | COC1=CC=C(C(N2C/C=C(C)\C)=C1)C3=C2[C@H](/C=C(C)\C)N(C([C@@]4([H])N5CCC4)=O)[C@]([C@H]3O)(O)C5=O |
| 分子式 | C27H33N3O5 |
| 分子量 | 479.6 |
| 溶解度 | DMSO: Soluble,Methanol: Soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Fumitremorgin B is a mycotoxin originally isolated fromA. fumigatus.1,2It induces tremors in and is lethal to mice (LD50= 5.4 mg/kg, i.v.). It is also toxic to brine shrimp (LC50= 13.6 μg/ml).3Fumitremorgin B is active against the phytopathogenic fungiB. cinerea,A. solani,A. alternata,C. gloeosporioides,F. solani,F. oxysporum, andG. saubinettii(MICs = 6.25-100 μg/ml). It has antifeedant activity against armyworm (M. separata) larvae when applied to fresh wheat leaves. Fumitremorgin B inhibits the proliferation of U937 and PC3 cells (IC50s = 14.12 and 43.36 μM, respectively).4 1.Yamazaki, M., Suzuki, S., and Miyaki, K.Tremorgenic toxins from Aspergillus fumigatus FresChem. Pharm. Bull. (Tokyo)19(8)1739-1740(1971) 2.Yamazaki, M., and Suzuki, S.Toxicology of tremorgenic mycotoxins, fumitremorgin A and BDev. Toxicol. Environ. Sci.12273-282(1986) 3.Li, X.-J., Zhang, Q., Zhang, A.-L., et al.Metabolites from Aspergillus fumigatus, an endophytic fungus associated with Melia azedarach, and their antifungal, antifeedant, and toxic activitiesJ. Agric. Food Chem.60(13)3424-3431(2012) 4.Wang, Y., Li, Z.-L., Bai, J., et al.2,5-diketopiperazines from the marine-derived fungus Aspergillus fumigatus YK-7Chem. Biodivers.9(2)85-93(2012) |
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