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1-Stearoyl-2-Arachidonoyl-d8-sn-glycero-3-PC
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
1-Stearoyl-2-Arachidonoyl-d8-sn-glycero-3-PC图片
CAS NO:161922-50-5
包装与价格：
包装价格(元)
50 μg电议
100 μg电议
500 μg电议
1mg电议

产品介绍
An internal standard for the quantification of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC
Cas No.161922-50-5
Canonical SMILES[O-]P(OC[C@H](OC(CCC/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)(OCC[N+](C)(C)C)=O
分子式C46H76D8NO8P
分子量818.2
溶解度Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

1-Stearoyl-2-arachidonoyl-d8-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC by GC- or LC-MS. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC) is a phospholipid containing stearic acid and arachidonic acid at thesn-1 andsn-2 positions, respectively. It is a component of LDL and has been found in human stenotic aortic valves and atherosclerotic plaques.1,2Levels of SAPC are increased in the subepithelial invasive region compared to the superficial region of tumor tissue samples from patients with superficial-type pharyngeal squamous cell carcinoma.3SAPC unilamellar vesicles have been used as substrates to quantify the activity of secretory phospholipase A2(sPLA2) in the presence or absence of inhibitors.4SAPC has also been used in the formation of lipid bilayers to study the effects of lipid composition on bilayer phase transitions.5

1.Milne, G.L., Seal, J.R., Havrilla, C.M., et al.Identification and analysis of products formed from phospholipids in the free radical oxidation of human low density lipoproteinsJ. Lipid Res.46(2)307-319(2005) 2.Lehti, S., KÄkelÄ, R., HÖrkkÖ, S., et al.Modified lipoprotein-derived lipid particles accumulate in human stenotic aortic valvesPLoS One8(6)e65810(2013) 3.Ishikawa, S., Tateya, I., Hayasaka, T., et al.The distribution of phosphatidylcholine species in superficial-type pharyngeal carcinomaBiomed. Res. Int.5387913(2017) 4.Schebb, N.H., Falck, D., Faber, H., et al.Fast method for monitoring phospholipase A2 activity by liquid chromatography-electrospray ionization mass spectrometryJ. Chromatogr. A1216(27)5249-5255(2009) 5.Tada, K., Goto, M., Tamai, N., et al.Pressure effect on the bilayer phase transition of asymmetric lipids with an unsaturated acyl chainAnn. N.Y. Acad. Sci.1189(1)77-85(2010)