| CAS NO: | 53-00-9 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
An active metabolite of dehydroepiandrosterone
| Cas No. | 53-00-9 |
| 别名 | 7-羟基去氢表雄酮 |
| Canonical SMILES | C[C@@]12[C@]3([H])[C@]([C@@H](C=C1C[C@H](CC2)O)O)([H])[C@@]4([H])[C@](CC3)(C(CC4)=O)C |
| 分子式 | C19H28O3 |
| 分子量 | 304.4 |
| 溶解度 | Ethanol: soluble |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 7α-hydroxy Dehydroepiandrosterone (7α-hydroxy DHEA) is an active metabolite of the endogenous steroid hormone dehydroepiandrosterone .17α-hydroxy DHEA is formed from dehydroepiandrosteronevia7-hydroxylation by cytochrome P450s (CYPs).2It increases antigen-induced production of anti-tetanus toxoid and anti-pertussis antigen IgGs in co-cultures of human tonsil-derived B and T cells when used at a concentration of 1 µM.37α-hydroxy DHEA (6.25 mg/kg) increases serum concentrations of anti-lysozyme IgG in mice.1 1.Morfin, R., and Courchay, G.Pregnenolone and dehydroepiandrosterone as precursors of native 7-hydroxylated metabolites which increase the immune response in miceJ. Steroid Biochem. Mol. Biol.50(1-2)91-100(1994) 2.Hampl, R., Morfin, R., and Starka, L.7-Hydroxylated derivatives of dehydroepiandrosterone: What are they good foroEndocr. Regul.31(4)211-218(1997) 3.Lafaye, P., Chmielewski, V., Nato, F., et al.The 7α-hydroxysteroids produced in human tonsils enhance the immune response to tetanus toxoid and Bordetella pertussis antigensBiochim. Biophys. Acta1472(1-2)222-231(1999) |
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