CAS NO: | 1232-73-1 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
Cas No. | 1232-73-1 |
Canonical SMILES | C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)O)([H])[C@@]4([H])[C@](CC3)(C([C@@H](C4)O)=O)C |
分子式 | C19H28O3 |
分子量 | 304.4 |
溶解度 | Chloroform: 10mg/ml |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 16α-hydroxy Dehydroepiandrosterone is a metabolite of the endogenous steroid hormone dehydroepiandrosterone .116α-hydroxy Dehydroepiandrosterone is formed from dehydroepiandrosteronevia16-hydroxylation by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5 in adult human liver microsomes, as well as by fetal recombinant CYP3A7. It is a precursor to fetal estrogens, including estriol .2 1.Miller, K.K.M., Cai, J., Ripp, S.L., et al.Stereo- and regioselectivity account for the diversity of dehydroepiandrosterone (DHEA) metabolites produced by liver microsomal cytochromes P450Drug. Metab. Dispos.32(3)305-313(2004) 2.Hampl, R., and Starka, L.Minireview: 16α-Hydroxylated metabolites of dehydroepiandrosterone and their biological significanceEndocr. Regul.34(3)161-163(2000) |