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16-Epiestriol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
16-Epiestriol图片
CAS NO:547-81-9
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议

产品介绍
16-Epiestriol 是内源性雌激素雌酮的代谢产物,具有抗菌和抗炎作用。
Cas No.547-81-9
别名异雌三醇,16-epi-Estriol; 16β,17β-Estriol
Canonical SMILESC[C@@]12[C@](C[C@@H]([C@@H]2O)O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(O)C=C4CC3
分子式C18H24O3
分子量288.4
溶解度Ethanol: 1 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

16-Epiestriol is a metabolite of the endogenous estrogen estrone .1It is formed from estroneviaa 16β-hydroxy estrone intermediate by reduction of the C-17 ketone. 16-Epiestriol (200 µg/ml) inhibits the growth of carbapenem-resistantA. baumannii.2It inhibits carrageenan-induced paw edema in rats when administered at a dose of 20 mg/kg.3Unlike hydrocortisone, 16-epiestriol (240 µg/animal) does not increase plasma or liver glucose levels in adrenalectomized rats.

1.Brinton, L.A., Trabert, B., Anderson, G.L., et al.Serum estrogens and estrogen metabolites and endometrial cancer risk among postmenopausal womenCancer Epidemiol. Biomarkers Prev.25(7)1081-1089(2016) 2.Skariyachan, S., Muddebihalkar, A.G., Badrinath, V., et al.Natural epiestriol-16 act as potential lead molecule against prospective molecular targets of multidrug resistant Acinetobacter baumannii-Insight from in silico modelling and in vitro investigationsInfect. Genet. Evol.82104314(2020) 3.Latman, N.S., Kishore, V., and Bruot, B.C.16-Epiestriol: An anti-inflammatory steroid without glycogenic activityJ. Pharm. Sci.83(6)874-877(1994)