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Desogestrel-13C2-d2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Desogestrel-13C2-d2图片
包装:1mg
市场价:6728元

产品介绍
An internal standard for the quantification of desogestrel
Canonical SMILESO[C@@]1([13C]#[13CH])C([2H])([2H])C[C@@]([C@]1(CC)C2)([H])[C@]3([H])CCC4=CCCC[C@]4([H])[C@@]3([H])C2=C
分子式C20[13C]2H28D2O
分子量314.5
溶解度Chloroform: slightly soluble,Methanol: very slightly soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Desogestrel-13C2-d2is intended for use as an internal standard for the quantification of desogestrel by GC- or LC-MS. Desogestrel is a synthetic progestogen.1It inhibits ovulation and prevents fertilization in rabbits and mice. Desogestrel inhibits rhodamine 123 efflux, a measure of P-glycoprotein activity,ex vivoin human lymphocytes and CD8+T cells in a dose-dependent manner.2Formulations containing desogestrel have been used as oral contraceptives and for the treatment of polycystic ovary syndrome.

1.van der Vies, J., and de Visser, J.Endocrinological studies with desogestrelArzneimittelforschung33(2)231-236(1983) 2.FrÖhlich, M., Albermann, N., Sauer, A., et al.In vitro and ex vivo evidence for modulation of P-glycoprotein activity by progestinsBiochem. Pharmacol.68(12)2409-2416(2004)