包装: | 1mg |
市场价: | 6728元 |
Canonical SMILES | O[C@@]1([13C]#[13CH])C([2H])([2H])C[C@@]([C@]1(CC)C2)([H])[C@]3([H])CCC4=CCCC[C@]4([H])[C@@]3([H])C2=C |
分子式 | C20[13C]2H28D2O |
分子量 | 314.5 |
溶解度 | Chloroform: slightly soluble,Methanol: very slightly soluble |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Desogestrel-13C2-d2is intended for use as an internal standard for the quantification of desogestrel by GC- or LC-MS. Desogestrel is a synthetic progestogen.1It inhibits ovulation and prevents fertilization in rabbits and mice. Desogestrel inhibits rhodamine 123 efflux, a measure of P-glycoprotein activity,ex vivoin human lymphocytes and CD8+T cells in a dose-dependent manner.2Formulations containing desogestrel have been used as oral contraceptives and for the treatment of polycystic ovary syndrome. 1.van der Vies, J., and de Visser, J.Endocrinological studies with desogestrelArzneimittelforschung33(2)231-236(1983) 2.FrÖhlich, M., Albermann, N., Sauer, A., et al.In vitro and ex vivo evidence for modulation of P-glycoprotein activity by progestinsBiochem. Pharmacol.68(12)2409-2416(2004) |