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Norethindrone-d6
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Norethindrone-d6图片
CAS NO:2376036-05-2
包装:5mg
市场价:5670元

产品介绍
An internal standard for the quantification of norethindrone
Cas No.2376036-05-2
别名炔诺酮D6,Norethisterone-d6
Canonical SMILESO=C1C([2H])([2H])C[C@@]2([2H])C(C([2H])([2H])C[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4(C#C)O)=C1[2H]
分子式C20H20D6O2
分子量304.5
溶解度Chloroform: slightly soluble,Methanol: slightly soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Norethindrone-d6is intended for use as an internal standard for the quantification of norethindrone by GC- or LC-MS. Norethindrone is a synthetic progestin.1In vivo, norethindrone (0.5 mg/animal per day) inhibits the estrous cycle in female mice. It induces tumor progression and metastasis in a BT474 breast cancer mouse xenograft model.2Formulations containing norethindrone have been used as oral contraceptives.

1.Bruce, H.M.Preliminary note on the effect of 19-norethisterone on mating behavior and fertility in the mouseProc. Soc. Study Fertility10158-165(1958) 2.Liang, Y., Benakanakere, I., Besch-Williford, C., et al.Synthetic progestins induce growth and metastasis of BT-474 human breast cancer xenografts in nude miceMenopause17(5)1040-1047(2010)