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7-hydroxy Chlorpromazine(hydrochloride)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
7-hydroxy Chlorpromazine(hydrochloride)图片
CAS NO:51938-11-5
包装:2.5mg
市场价:3916元

产品介绍
An active metabolite of chlorpromazine
Cas No.51938-11-5
Canonical SMILESClC1=CC=C2SC3=CC(O)=CC=C3N(CCCN(C)C)C2=C1.Cl
分子式C17H19ClN2OS•HCl
分子量371.3
溶解度Methanol: slightly soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

7-hydroxy Chlorpromazine is an active metabolite of the typical antipsychotic chlorpromazine .1In vivo, 7-hydroxy chlorpromazine (5 mg/kg) increases plasma prolactin levels in male rats. It also reverses D-amphetamine-induced depression of the dopaminergic neuronal firing rate in the rat substantia nigra in rats when administered at a dose of 1.6 mg/kg.2

1.Meltzer, H.Y., Fang, V.S., Simonovich, M., et al.Effect of metabolites of chlorpromazine on plasma prolactin levels in male ratsEur. J. Pharmacol.41(4)431-436(1977) 2.Bunney, B.S., and Aghajanian, G.K.A comparison of the effects of chlorpromazine, 7-hydroxychlorpromazine and chlorpromazine sulfoxide on the activity of central dopaminergic neuronsLife Sci.15(2)309-318(1974)