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Progesterone-d9
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Progesterone-d9图片
CAS NO:15775-74-3
包装:1mg
市场价:2102元

产品介绍
An internal standard for the quantification of progesterone
Cas No.15775-74-3
别名氘代黄体酮/氘代4-烯-3,20-二酮,Pregn-4-ene-3,20-dione-d9
Canonical SMILESC[C@@]12[C@](CC[C@]2([2H])C(C([2H])([2H])[2H])=O)([H])[C@]3([H])CC([2H])([2H])C4=C([2H])C(C([2H])([2H])C[C@]4(C)[C@@]3([H])CC1)=O
分子式C21H21D9O2
分子量323.5
溶解度Acetonitrile: 1 mg/ml,Ethanol: 1 mg/ml,Methanol: 1 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Progesterone-d9is intended for use as an internal standard for the quantification of progesterone by GC- or LC-MS. Progesterone is the biosynthetic precursor of all other steroid hormones.1Progesterone is synthesized from cholesterol by the sequential action of desmolase in the mitochondria, which produces pregnenolone, followed by δ4,5-isomerase in the outer mitochondrial membrane and smooth endoplasmic reticulum of steroid-secreting cells. Progesterone activates the human progesterone receptor with an EC50value of 0.5 nM.2

1.Erickson, G.F.The ovary: Basic principles and concepts. A. PhysiologyEndocrinology and Metabolism3rd ed.973-1015(1995) 2.Pedram, B., van Oeveren, A., Mais, D.E., et al.A tissue-selective nonsteroidal progesterone receptor modulator: 7,9-Difluoro-5-(3-methylcyclohex-2-enyl)-2,2,4-trimethyl-1,2-dihydrochromeno[3,4-f]quinolineJ. Med. Chem.51(13)3696-3699(2008)