CAS NO: | 15775-74-3 |
包装: | 1mg |
市场价: | 2102元 |
Cas No. | 15775-74-3 |
别名 | 氘代黄体酮/氘代4-烯-3,20-二酮,Pregn-4-ene-3,20-dione-d9 |
Canonical SMILES | C[C@@]12[C@](CC[C@]2([2H])C(C([2H])([2H])[2H])=O)([H])[C@]3([H])CC([2H])([2H])C4=C([2H])C(C([2H])([2H])C[C@]4(C)[C@@]3([H])CC1)=O |
分子式 | C21H21D9O2 |
分子量 | 323.5 |
溶解度 | Acetonitrile: 1 mg/ml,Ethanol: 1 mg/ml,Methanol: 1 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Progesterone-d9is intended for use as an internal standard for the quantification of progesterone by GC- or LC-MS. Progesterone is the biosynthetic precursor of all other steroid hormones.1Progesterone is synthesized from cholesterol by the sequential action of desmolase in the mitochondria, which produces pregnenolone, followed by δ4,5-isomerase in the outer mitochondrial membrane and smooth endoplasmic reticulum of steroid-secreting cells. Progesterone activates the human progesterone receptor with an EC50value of 0.5 nM.2 1.Erickson, G.F.The ovary: Basic principles and concepts. A. PhysiologyEndocrinology and Metabolism3rd ed.973-1015(1995) 2.Pedram, B., van Oeveren, A., Mais, D.E., et al.A tissue-selective nonsteroidal progesterone receptor modulator: 7,9-Difluoro-5-(3-methylcyclohex-2-enyl)-2,2,4-trimethyl-1,2-dihydrochromeno[3,4-f]quinolineJ. Med. Chem.51(13)3696-3699(2008) |