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Estrone-d2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Estrone-d2图片
CAS NO:350820-16-5
包装与价格:
包装价格(元)
500μg电议
1mg电议

产品介绍
 
Cas No.350820-16-5
别名雌酚酮-D2,E1-d2; Oestrone-d2
Canonical SMILESO=C1CC[C@@]2([H])[C@]3([H])CCC4=C([2H])C(O)=C([2H])C=C4[C@@]3([H])CC[C@@]21C
分子式C18H20D2O2
分子量272.4
溶解度DMF: 30 mg/mL,DMF:PBS (pH 7.2) (1:5): 0.15 mg/mL,DMSO: 20 mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Estrone-d2 is intended for use as an internal standard for the quantification of estrone by GC- or LC-MS. Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol .1 Estrone is synthesized from androstenedione by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by 17-hydroxy steroid dehydrogenase in the liver.1,2 Serum concentrations of estrone in premenopausal women fluctuate according to the menstrual cycle and becomes the most predominant estrogen in postmenopausal women.1 The binding affinities of estrone to the estrogen receptors α and β are approximately 60% and 37% relative to estradiol.1

References
1. Gruber, C.J., Tschugguel, W., Schneeberger, C., et al. Production and actions of estrogens. New England Journal of Medicine 346(5), 340-352 (2002).