IL-15-IN-1是有效,选择性的抑制剂,抑制IL-15依赖性细胞的 IC50 为0.8 μM。
产品描述 | IL-15-IN-1 is a potent and selective Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells with an IC50 of 0.8 μM. [1]. QuÉmÉner A, et al. Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization. J Med Chem. 2017 Jul 27;60(14):6249-6272. |