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AXC-715 trihydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AXC-715 trihydrochloride图片
CAS NO:2479276-17-8
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
AXC-715 (T785) trihydrochloride 是一种 TLR7/TLR8 双激动剂,从专利 WO2020168017 A1 中获得。AXC-715 trihydrochloride 可用于合成抗体佐剂免疫偶联物,偶联物包括一个与程序性死亡配体 1 (PD-L1) 连接到一个或多个佐剂的抗体结构上。
Cas No.2479276-17-8
别名T785 trihydrochloride
分子式C18H28Cl3N5
分子量420.81
溶解度DMSO : 125 mg/mL (297.05 mM; Need ultrasonic)
储存条件4°C, away from moisture
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

AXC-715 (T785) trihydrochloride is a TLR7/TLR8 dual agonist, extracted from patent WO2020168017 A1[1]. AXC-715 trihydrochloride, compound D from WO2020190734A1, can be used for synthesis of antibody-adjuvant immunoconjugates, comprising an antibody construct that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants[2].

[1]. Sung-Ju Moon, et al. Compositions containing, methods and uses of antibody-tlr agonist conjugates. Patent WO2020168017A1.
[2]. Shelley Erin ACKERMAN, et al. Immunoconjugates targeting pd-l1. Patent WO2020190734A1.