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Dimidium(bromide)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dimidium(bromide)图片
CAS NO:518-67-2
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议
250mg电议

产品介绍
A trypanocide
Cas No.518-67-2
别名溴化底米鎓
Canonical SMILESNC1=CC2=C(C3=C([N+](C)=C2C4=CC=CC=C4)C=C(N)C=C3)C=C1.[Br-]
分子式C20H18N3 • Br
分子量380.3
溶解度DMF: 2 mg/ml,DMSO: 3 mg/ml,Ethanol: insol,PBS (pH 7.2): insol
储存条件-20буC
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dimidium is a trypanocide.1,2In vivo, dimidium (0.25-0.7 mg/kg) reduces parasite burden inT. congolense-infected mice.1It also completely clears trypanosomes from the peripheral blood in zebu oxen naturally infected withT. congolensewhen administered intramuscularly at a dose of 0.75 mg/kg.2Formulations containing dimidium have previously been used in the treatment of trypanosomiasis in cattle.

1.Woolfe, G.The trypanocidal action of phenanthridine compoundsAnn. Trop. Med. Parasitol.46(4)285-288(1952) 2.Wilde, J.K.H.Experimental use of dimidium bromide (1553) in the treatment of T. congolense infection in the zebu cattleJ. Comp. Pathol. Ther.59(1)48-53(1949)