| CAS NO: | 32434-42-7 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| Cas No. | 32434-42-7 |
| 别名 | 常山乙素二盐酸盐 |
| Canonical SMILES | O=C1C2=CC=CC=C2N=CN1CC(C[C@H]3NCCC[C@@H]3O)=O.Cl.Cl |
| 分子式 | C16H19N3O3 • 2HCl |
| 分子量 | 374.3 |
| 溶解度 | Acetone: soluble,Chloroform: soluble,DMSO: soluble,Ethyl Acetate: soluble |
| 储存条件 | -20буC |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Febrifugine is a quinazolinone alkaloid originally isolated fromD. febrifugathat has antimalarial activity.1,2It reduces parasitemia and decreases mortality in mice infected with theP. bergheistrain NK65 when administered at a dose of 1 mg/kg per day beginning prior to or on the day of infection.3 1.Koepfli, J.B., Mead, J.F., and Brockman, J.A., Jr.An alkaloid with high antimalarial activity from Dichroa febrifugaJ. Am. Chem. Soc.69(7)1837(1947) 2.McLaughlin, N.P., Evans, P., and Pines, M.The chemistry and biology of febrifugine and halofuginoneBioorg. Med. Chem.22(7)1993-2004(2014) 3.Murata, K., Takano, F., Fushiya, S., et al.Potentiation by febrifugine of host defense in mice against Plasmodium berghei NK65Biochem. Pharmacol.58(10)1593-1601(1999) |
m.cnreagent.com