包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
Canonical SMILES | O=C1N(C([2H])([2H])[2H])C(C(N(CCO)C=N2)=C2N1C([2H])([2H])[2H])=O |
分子式 | C9H6D6N4O3 |
分子量 | 230.3 |
溶解度 | Chloroform: soluble,Methanol: soluble |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 7-(β-Hydroxyethyl)theophylline-d6is intended for use as an internal standard for the quantification of 7-(β-hydroxyethyl)theophylline by GC- or LC-MS. 7-(β-Hydroxyethyl)theophylline is a methylxanthine phosphodiesterase (PDE) inhibitor.1It reduces histamine, 5-hydroxytryptamine (5-HT), and bradykinin-induced bronchoconstriction in an anesthetized guinea pig model of bronchial asthma.2Formulations containing 7-(β-hydroxyethyl)theophylline in combination with theophylline have been used in the treatment of asthma. 1.Mizon, J., Skandrani, E., and Mizon, C.Determination of the inhibitory activity of some new substituted theophyllines on the specific phosphodiesterase of cyclic nucleotidesTherapie26(5)911-917(1971) 2.Ufkes, J.G., Leeuwin, R.S., Ottenhof, M., et al.Efficacy of theophylline and its N-7-substituted derivatives in experimentally induced bronchial asthma in the guinea-pigArch. Int. Pharmacodyn. Ther.253(2)301-314(1981) |