CAS NO: | 22601-59-8 |
包装 | 价格(元) |
500 µg | 电议 |
1mg | 电议 |
5mg | 电议 |
Cas No. | 22601-59-8 |
别名 | 杆菌肽A |
Canonical SMILES | O=C(N[C@@H](C(N[C@@](C(N[C@@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(NCCCC1)=O)CC(N)=O)=O)CC(O)=O)=O)CC2=CN=CN2)=O)CC3=CC=CC=C3)=O)([H])[C@@H](C)CC)=O)CCCN)[C@H]1NC([C@H]([C@@H](C)CC)NC([C@@H](CCC(O)=O)NC([C@H](CC(C)C)NC([C@@H]4CSC([C@@H](N)[C@H](CC)C)=N4)=O)=O)=O)=O |
分子式 | C66H103N17O16S |
分子量 | 1422.7 |
溶解度 | DMSO: slightly soluble,Methanol: slightly, sonicated |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Bacitracin A is a polypeptide antibiotic that has been found inB. licheniformisand the main active component of the bacitracin family of polypeptide antibiotics.1It is active againstM. lysodeikticuswhen used at a concentration of 0.1 µM and forms a complex with divalent cations and the cell membrane component C55-isoprenyl pyrophosphate.2Bacitracin A is also active against the plant pathogenic bacteriaP. ananatiswith a median effective concentration (MEC) of 9.1 µg/ml.3It induces cell wall damage and cell leakage inP. ananatis. 1.Newton, G.G.F., and Abraham, E.P.Observations on the nature of bacitracin ABiochem. J.53(4)604-613(1953) 2.Storm, D.R., and Strominger, J.L.Complex formation between bacitracin peptides and isoprenyl pyrophosphates. The specificity of lipid-peptide interactionsJ. Biol. Chem.248(11)3940-3945(1973) 3.Jin, P., Tan, Z., Wang, H., et al.Antimicrobial effect of Bacillus licheniformis HN-5 bacitracin A on rice pathogen Pantoea ananatisBioControl66249-257(2020) |