CAS NO: | 129639-79-8 |
包装 | 价格(元) |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
Cas No. | 129639-79-8 |
别名 | 阿巴芬净,BAY-W-6341 |
Canonical SMILES | CC1=CC(C)=CC=C1OC2=C(C=CC=C2)C3=CSC(NC4=NCCCN4)=N3 |
分子式 | C21H22N4OS |
分子量 | 378.5 |
溶解度 | DMF: 10 mg/mL,DMSO: 2.5 mg/mL,Ethanol: 0.3 mg/mL,PBS (pH 7.2): 0.3 mg/mL |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Abafungin is an antifungal agent.1It is active against a variety of dermatophytes, yeast, molds, and other fungi (MICs = ≤0.06-2, 0.5-16, ≤0.06-1, and 0.25-8 µg/ml, respectively). Abafungin inhibits ergosterol biosynthesis, as well as acts directly on the fungal cell membrane to induce cell death. 1.Borelli, C., Schaller, M., Niewerth, M., et al.Modes of action of the new arylguanidine abafungin beyond interference with ergosterol biosynthesis and in vitro activity against medically important fungiChemotherapy54(4)245-259(2022) |