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C3
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
C3图片
CAS NO:2286257-25-6
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
An inhibitor of MAO-B
Cas No.2286257-25-6
Canonical SMILESNC([C@H](CC1)N1CC2=CC=C(C=C2)OCC3=CC(F)=CC=C3)=O
分子式C18H19FN2O2
分子量314.4
溶解度DMF: 15 mg/ml,DMSO: 2 mg/ml,Ethanol: 2 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

C3 is an inhibitor of monoamine oxidase B (MAO-B; IC50= 0.021 µM).1It is selective for MAO-B over MAO-A (IC50= 26.8 µM). C3 (0.1, 1, and 3 mg/kg) prevents MPTP-induced decreases in brain dopamine levels in mice.

1.Jin, C.-F., Wang, Z.-Z., Chen, K.-Z., et al.Computational fragment-based design facilitates discovery of potent and selective monoamine oxidase-B (MAO-B) inhibitorJ. Med. Chem.63(23)15021-15036(2020)