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Levomedetomidine(hydrochloride)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Levomedetomidine(hydrochloride)图片
CAS NO:190000-46-5
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
The levorotary enantiomer of medetomidine
Cas No.190000-46-5
别名盐酸左美托咪定
Canonical SMILESC[C@@H](C1=CN=CN1)C2=C(C(C)=CC=C2)C.Cl
分子式C13H16N2• HCl
分子量236.7
溶解度DMF: 20 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 1 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Levomedetomidine is the levorotary enantiomer of the racemic α2-adrenergic receptor (α2-AR) agonist medetomidine.1Unlike medetomidine or the dextrorotary enantiomer dexmedetomidine , levomedetomidine does not induce sedation or analgesia when administered alone in dogs.2However, levomedetomidine does reduce the level of dexmedetomidine-induced sedation in dogs. Formulations containing levomedetomidine have been used as anesthetics.

1.Kim, S.M., Lee, B., An, H.J., et al.Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during agingOncotarget8(28)46273-46285(2017) 2.Kuusela, E., Vainio, O., Kaistinen, A., et al.Sedative, analgesic, and cardiovascular effects of levomedetomidine alone and in combination with dexmedetomidine in dogsAm. J. Vet. Res.62(4)616-621(2001)