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2-Aminotetralin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
2-Aminotetralin图片
CAS NO:2954-50-9
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议
1 g电议

产品介绍
A neuromodulatory agent
Cas No.2954-50-9
别名1,2,3,4-四氢-2-萘胺
Canonical SMILESNC1CC2=CC=CC=C2CC1
分子式C10H13N
分子量147.2
溶解度DMSO: soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2-Aminotetralin is a neuromodulatory agent.1,2,3It inhibits serotonin (5-HT) and norepinephrine reuptake in rat brain when administered at a dose of 39.4 mg/kg.12-Aminotetralin induces hypothermia in rats when administered by intracisternal or intraperitoneal injection, but implantation of 2-aminotetralin crystals in the medial preoptic area of the hypothalamus induces hyperthermia in rats.2It substitutes for (+)-amphetamine in rats in a two-lever drug discrimination test in a dose-dependent manner.3

1.Bruinvels, J.Evidence for inhibition of the reuptake of 5-hydroxytryptamine and noradrenaline by tetrahydronaphthylamine in rat brainBr. J. Pharmacol.42(2)281-286(1971) 2.Bruinvels, J., and Kemper, G.C.Role of noradrenaline and 5-hydroxytryptamine in tetrahydronaphthylamine-induced temperature changes in the ratBr. J. Pharmacol.43(1)1-9(1971) 3.Oberlender, R., and Nichols, D.E.Structural variation and (+)-amphetamine-like discriminative stimulus propertiesPharmacol. Biochem. Behav.38(3)581-586(1991)