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Tivanisiran
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1848224-71-4
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
Tivanisiran (SYL1001) 是一种 siRNA,可用于干眼症的研究。Tivanisiran 用于沉默TRPV1。
Cas No.1848224-71-4
别名SYL1001
储存条件Store at -20°C, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Tivanisiran (SYL1001) is a siRNA used for the study of dry eye disease. Tivanisiran was designed to silence transient receptor potential vanilloid 1 (TRPV1)[1].

In vitro transfection of tivanisiran was shown to produce a 50-60% decrease in TRPV1 mRNA levels[1][2].

[1]. Anne-Marie Bleau, et al. Development of tivanisiran, a topical siRNA designed to
[2]. Javier Moreno-MontaÑÉs, et al. Tivanisiran, a novel siRNA for the treatment of dry eye disease. Expert Opin Investig Drugs. 2018 Apr;27(4):421-426.