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Dirocaftor
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dirocaftor图片
CAS NO:2137932-23-9
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
Dirocaftor (PTI-808) 是一种 CFTR 增效剂,通过打开氯离子通道来增强 CFTR 蛋白的功能。Dirocaftor 可用于囊性纤维化 (CF) 的研究。
Cas No.2137932-23-9
分子式C22H28N2O3Si2
分子量424.64
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dirocaftor (PTI-808) is a CFTR potentiator that enhances the function of CFTR protein by opening chloride channels. Dirocaftor can be used for cystic fibrosis (CF) research[1][2].

When combined with Nesolicaftor and Posenacaftor, Dirocaftor can restore CFTR function to nearly normal levels[2].

[1]. James A Reihill, et al. Modulation of Ion Transport to Restore Airway Hydration in Cystic Fibrosis. Genes (Basel). 2021 Mar 22;12(3):453.
[2]. P. van Mourik, et al. WS10 Moving beyond body mass index to assess nutritional status in CF. Journal of Cystic Fibrosis 19S2 (2020) S1-S36.