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(Rac)-CP-601927 hydrochloride
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
(Rac)-CP-601927 hydrochloride图片
CAS NO:230615-01-7
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
(Rac)-CP-601927 hydrochloride 是 CP-601927 的外消旋物。CP-601927 是一种 nAChR 激动剂，对 α4β2 和 α3β4 nAChR 的 Ki 值分别为 1.2 nM 和 102 nM。
Cas No.230615-01-7
分子式C12H13ClF3N
分子量263.69
储存条件4°C, away from moisture
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(Rac)-CP-601927 hydrochloride is the racemate of CP-601927. CP-601927 is a nAChR agonist with Ki values 1.2 nM and 102 nM for α4β2 and α3β4 nAChR, respectively[1].

CP-601927 induces significant antidepressant-like effects in mice. CP-601927 could decrease cholinergic signaling as a result of its reduced efficacy or via desensitization of α4β2* nAChRs[1].

[1]. Yann S Mineur, et al. α4β2 nicotinic acetylcholine receptor partial agonists with low intrinsic efficacy have antidepressant-like properties. Behav Pharmacol. 2011 Aug;22(4):291-9.