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rac-N-desmethyl Ivabradine-d6(hydrochloride)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
rac-N-desmethyl Ivabradine-d6(hydrochloride)图片
包装:1mg
市场价:6804元

产品介绍
An internal standard for the quantification of N-desmethyl ivabradine
Canonical SMILESCOC1=CC(CCN2C([2H])([2H])C([2H])([2H])C([2H])([2H])NC[C@@H]3C4=CC(OC)=C(C=C4C3)OC)=C(CC2=O)C=C1OC.Cl
分子式C26H28D6N2O5·HCl
分子量497.1
溶解度Methanol: soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

rac-N-desmethyl Ivabradine-d6is intended for use as an internal standard for the quantification of N-desmethyl ivabradine by GC- or LC-MS. N-desmethyl Ivabradine is an active metabolite of ivabradine .1Ivabradine is metabolized by the cytochrome P450 (CYP) isoform CYP3A4.

1.Rosa, G.M., Ferrero, S., Ghione, P., et al.An evaluation of the pharmacokinetics and pharmacodynamics of ivabradine for the treatment of heart failureExpert Opin. Drug Metab. Toxicol.10(2)279-291(2014)