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Trifluoperazine N-Glucuronide
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Trifluoperazine N-Glucuronide图片
CAS NO:165602-90-4
包装与价格：
包装价格(元)
500 µg电议
1mg电议

产品介绍
Trifluoperazine N-Glucuronide (UGT1A4) 作为人类 UGT1A 亚型之一，在肝脏中表达。
Cas No.165602-90-4
别名三氟拉嗪N-Β-D-葡糖苷酸,UGT1A4
Canonical SMILESC[N+](CC1)([C@H]2[C@H](O)[C@@H](O)[C@@H]([C@@H](C([O-])=O)O2)O)CCN1CCCN3C4=CC(C(F)(F)F)=CC=C4SC5=CC=CC=C53
分子式C27H32F3N3O6S
分子量583.6
溶解度Methanol: soluble,Water: soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Trifluoperazine N-glucuronide is a metabolite of the antipsychotic agent trifluoperazine .1,2It is formed from trifluoperazine by the UDP-glucuronosyltransferase (UGT) isoform UGT1A4.2

1.Luo, H., Hawes, E.M., McKay, G., et al.N(+)-glucuronidation of aliphatic tertiary amines in human: antidepressant versus antipsychotic drugsXenobiotica25(3)291-301(1995) 2.Fujiwara, R., Nakajima, M., Yamanaka, H., et al.Interactions between human UGT1A1, UGT1A4, and UGT1A6 affect their enzymatic activitiesDrug Metab. Dispos.35(10)1781-1787(2007)