| CAS NO: | 106021-96-9 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| Cas No. | 106021-96-9 |
| 别名 | H2N-Val-Gln-Gly-Glu-Glu-Ser-Asn-Asp-Lys-OH |
| 化学名 | β-Interleukin I (163-171), human |
| Canonical SMILES | CC(C)C(C(=O)NC(CCC(=O)N)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)NC(CC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)O)N |
| 分子式 | C39H64N12O19 |
| 分子量 | 1004.99 |
| 溶解度 | ≥ 100.4mg/mL in DMSO |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | β-Interleukin I (163-171), human(C39H64N12O19), a peptide with the sequence Val-Gln-Gly-Glu-Glu-Ser-Asn-Asp-Lys, MW= 1005.Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes). Interleukin 1 alpha and interleukin 1 beta (IL-1 alpha and IL-1 beta) are cytokines that participate in the regulation of immune responses, inflammatory reactions, and hematopoiesis. Interleukin-1 beta (IL-1β) also known as catabolin, is a cytokine protein that in humans is encoded by theIL1Bgene. IL-1β precursor is cleaved by caspase 1 (interleukin 1 beta convertase). Cytosolic thiol protease cleaves the product to form mature IL-1β. IL-1β is a member of the interleukin 1 cytokine family. This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.
Figure1 Formula of b-Interleukin I (163-171), human
Figure2 Structure of b-Interleukin I Ref: 1. Contassot E, Beer HD, French LE (2012). "Interleukin-1, inflammasomes, autoinflammation and the skin".Swiss Med Wkly142: w13590 2. Matzinger P (2012). "The evolution of the danget theory. Interview by Lauren Constable, Commissioning Editor".Expert Rev Clin Immunol8(4): 311-7. 3. Sahoo M, Ceballos-Olvera I, del Barrio L, Re F (2011). "Role of the inflammasome, IL-1β, and IL-18 inbacterial infections".ScientificWorldJournal11: 2037-50.
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