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β-Interleukin I(163-171),human
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
β-Interleukin I(163-171),human图片
CAS NO:106021-96-9
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
T cell activator
Cas No.106021-96-9
别名H2N-Val-Gln-Gly-Glu-Glu-Ser-Asn-Asp-Lys-OH
化学名β-Interleukin I (163-171), human
Canonical SMILESCC(C)C(C(=O)NC(CCC(=O)N)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)NC(CC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)O)N
分子式C39H64N12O19
分子量1004.99
溶解度≥ 100.4mg/mL in DMSO
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

β-Interleukin I (163-171), human(C39H64N12O19), a peptide with the sequence Val-Gln-Gly-Glu-Glu-Ser-Asn-Asp-Lys, MW= 1005.Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes). Interleukin 1 alpha and interleukin 1 beta (IL-1 alpha and IL-1 beta) are cytokines that participate in the regulation of immune responses, inflammatory reactions, and hematopoiesis.

Interleukin-1 beta (IL-1β) also known as catabolin, is a cytokine protein that in humans is encoded by theIL1Bgene. IL-1β precursor is cleaved by caspase 1 (interleukin 1 beta convertase). Cytosolic thiol protease cleaves the product to form mature IL-1β. IL-1β is a member of the interleukin 1 cytokine family. This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.

A1026_1 

Figure1 Formula of b-Interleukin I (163-171), human

A1026_2 

Figure2 Structure of b-Interleukin I 

Ref:

1. Contassot E, Beer HD, French LE (2012). "Interleukin-1, inflammasomes, autoinflammation and the skin".Swiss Med Wkly142: w13590

2. Matzinger P (2012). "The evolution of the danget theory. Interview by Lauren Constable, Commissioning Editor".Expert Rev Clin Immunol8(4): 311-7.

3. Sahoo M, Ceballos-Olvera I, del Barrio L, Re F (2011). "Role of the inflammasome, IL-1β, and IL-18 inbacterial infections".ScientificWorldJournal11: 2037-50.