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TCO-PEG3-amine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
TCO-PEG3-amine图片
CAS NO:1800507-93-0
包装与价格:
包装价格(元)
25mg电议
100mg电议
250mg电议

产品介绍
TCO-PEG3-amine 是一种 PROTAC linker,属于 PEG 类。TCO-PEG3-amine 可用于合成一系列 PROTAC 分子。
Cas No.1800507-93-0
分子式C17H32N2O5
分子量344.45
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

TCO-PEG3-amine is a PEG-basedPROTAC linkercan be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.