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BIO-acetoxime
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BIO-acetoxime图片
CAS NO:667463-85-6
包装与价格:
包装价格(元)
2mg电议
5mg电议

产品名称
MolPort-023-276-964, 667463-85-6, AKOS024457841, AKOS025295610
产品介绍

生物活性

BIO-acetoxime是一种有效的双重GSK3α/β抑制剂,IC50为10 nM,选择性比CDK5/p25,CDK2/cyclin A和 CDK1/cyclin B高240倍以上。

靶点信息

GSK-3αGSK-3β
10 nM10 nM

化学数据

目录号A15555
作用机制Inhibitor (抑制剂)
M. Wt398.21
FormulaC18H12BrN3O3
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.667463-85-6
SynonymsMolPort-023-276-964, 667463-85-6, AKOS024457841, AKOS025295610
SMILESCC(=O)ONC1=C2C=CC=CC2=NC1=C3C4=C(C=C(C=C4)Br)NC3=O

溶解度

In vitroDMSOWarmed: 18 mg/mL (45.2 mM)
WaterInsoluble
EthanolInsoluble
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM25.11 mL125.56 mL251.12 mL
0.5 mM5.02 mL25.11 mL50.22 mL
1 mM2.51 mL12.56 mL25.11 mL
5 mM0.5 mL2.51 mL5.02 mL

*The above data is based on the productmolecular weight 398.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.