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23-epi-26-Deoxyactein
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
23-epi-26-Deoxyactein图片
CAS NO:264624-38-6
包装与价格:
包装价格(元)
500μg电议
1mg电议
5mg电议

产品介绍
23-epi-26-Deoxyactein 是一种从总状升麻中分离出来的成分,可防止 TCDD 诱导的成骨细胞损伤。
Cas No.264624-38-6
别名脱氧升麻烃,27-Deoxyactein
Canonical SMILESC[C@](CO1)(O2)[C@@H]2[C@@]31O[C@@]4([H])C[C@@]5(C)[C@]6([H])CC[C@]7([H])[C@]8(CC[C@H](O[C@]9([H])OC[C@@H](O)[C@H](O)[C@H]9O)C7(C)C)[C@]6(C8)C[C@@H](OC(C)=O)[C@]5(C)[C@@]4([H])[C@H](C)C3
分子式C37H56O10
分子量660.8
溶解度Water: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

23-epi-26-Deoxyactein is a triterpene glycoside and a major constituent of black cohosh (C. racemosa). It reduces intracellular calcium concentrations, collapse of the mitochondrial membrane potential, production of reactive oxygen species (ROS), and cardiolipin peroxidation and inhibits autophagy and apoptosis in osteoblastic MC3T3-E1 cells induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). 23-epi-26-Deoxyactein (0.01-10 μM) reduces production of ROS and IL-1β and cell death induced by methylglyoxal in RIN-m5F β-cells.