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3',4',7-Trihydroxyisoflavone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
3',4',7-Trihydroxyisoflavone图片
CAS NO:485-63-2
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议
250mg电议

产品介绍
3',4',7-Trihydroxyisoflavone 是黄豆苷元的主要代谢物,是 Cot (Tpl2/MAP3K8) 和 MKK4 的 ATP 竞争性抑制剂。 3',4',7-三羟基异黄酮具有抗癌、抗血管生成、化学保护和自由基清除活性。
Cas No.485-63-2
别名3',4',7-三羟基异黄酮
Canonical SMILESOC1=CC=C(C(C(C2=CC(O)=C(O)C=C2)=CO3)=O)C3=C1
分子式C15H10O5
分子量270.2
溶解度DMF: 20 mg/ml,DMF:PBS (pH 7.2) (1:4): 0.1 mg/ml,DMSO: 10 mg/ml,Ethanol: 1 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

3',4',7-Trihydroxyisoflavone is a natural isoflavonoid that has antioxidant activity. It can be produced by the metabolism of daidzein or daidzin . 3',4',7-Trihydroxyisoflavone inhibits several signaling pathways in cells, including tyrosinase-mediated melanin formation (IC50 = 5.2 µM), casein kinase II-mediated phosphorylation of 60S acidic ribosomal P proteins, and cyclin-dependent, kinase-regulated cell proliferation.