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3,3′-Dioctadecyloxacarbocyanine perchlorate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
3,3′-Dioctadecyloxacarbocyanine perchlorate图片
CAS NO:34215-57-1
包装:5mg
市场价:698元

产品介绍
3,3′-Dioctadecyloxacarbocyanine perchlorate 是一种绿色荧光亲油性示踪剂,它在水中发出微弱的荧光,但在掺入膜时具有高荧光和相当光稳定性。
Cas No.34215-57-1
别名3-十八烷基-2-[3-(3-十八烷基-2(3H)-苯并恶唑-2-亚基)-1-丙烯-1-基]苯并恶唑高氯酸盐,DiO; DiOC18(3)
Canonical SMILESO=Cl(=O)([O-])=O.CCCCCCCCCCCCCCCCCCN1C(C=CC=C2)=C2O/C1=C/C=C/C(OC3=C4C=CC=C3)=[N+]4CCCCCCCCCCCCCCCCCC
分子式C53H85ClN2O6
分子量881.70
溶解度Soluble in DMSO
储存条件Store at 4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

3,3′-Dioctadecyloxacarbocyanine perchlorate is a green fluorescent lipophilic tracer, which is weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes.

A fluorescent dialkyl carbocyanine dye (DiOC18(3)) is used to label muscle membranes, and the membranes accessible to the dye were observed by confocal laser scanning microscopy. A loss of cell membrane integrity results from contractile activity, enabling DiOC18(3) staining of internal membranes. The resulting staining pattern is striking and fibers with damaged cell membranes are easily distinguished from uninjured ones[1]. 3,3′-Dioctadecyloxacarbocyanine perchlorate is a cationic oxacarbocyanine dye. The absorption and fluorescence spectra of 3,3'-dioctadecyloxacarbocyanine, a cationic oxacarbocyanine dye have been studied in aqueous and nonaqueous media containing egg phosphatidylcholine (PC) as well as in different solvents of diverse nature. The results show the evidence of complex formation of the dye in the ground and in the excited states with PC. The excited state interaction of the dye with PC suggests the electron transfer from PC to dye and this is supported by photovoltage generation in a photoelectrochemical cell consisting of dye and PC in aqueous medium[2].

Reference:

[1]. Warren GL, et al. Redistribution of cell membrane probes following contraction-induced injury of mouse soleus muscle.
[2]. Bhowmik BB, et al. Photophysical studies of 3,3' dioctadecyloxacarbocyanine dye in model biological membranes and different solvents. Chem Phys Lipids. 2001 Feb;109(2):175-83.