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BR102910
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BR102910图片
CAS NO:2505339-54-6
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
BR102910 是一种选择性的成纤维细胞活化蛋白 (FAP) 抑制剂,IC50 为 2 nM。BR102910 还抑制脯氨酰寡肽酶 (PREP),IC50 为 49.00 μM。BR102910可用于2型糖尿病的研究。
Cas No.2505339-54-6
别名(S)-N-[2-(2-氰基-4,4-二氟吡咯烷-1-基)-2-氧代乙基]-2-[(3,4-二氯苄基)噻唑-4-甲酰胺
分子式C18H14Cl2F2N4O2S
分子量459.3
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

BR102910 is a selective fibroblast activation protein (FAP) inhibitor with the IC50 of 2 nM. BR102910 also inhibits prolyl oligopeptidase (PREP) with the IC50 of 49.00 μM. BR102910 can be used for the researchof type 2

BR102910 (C57BL/6J mice, 0-30 mg/kg, Orally, once) shows significant FAP inhibition in a dose dependent manner[1].

[1]. Hui Jin Jung, et al. Identification of BR102910 as a selective fibroblast activation protein (FAP) inhibitor. Bioorg Med Chem Lett. 2021 Apr 1;37:127846.