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ICI-D7114
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ICI-D7114图片
CAS NO:129689-28-7
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
250mg电议
500mg电议

产品介绍
ICI-D7114 (also known as ZD7114) is a novel, potent and selective beta-adrenoceptor agonist of brown fat and thermogenesis. It has the promise in the treatment of obesity. ICI D7114 stimulates whole body oxygen consumption in conscious rats, cats and dogs and brown adipose tissue (BAT) activity in conscious rats. Treatment of rats with ICI D7114 stimulated oxygen consumption (ED50, 0.04 mg kg-1, p.o.) and BAT mitochondrial guanosine diphosphate (GDP)-binding (ED50, 0.15 mg kg-1, p.o.) with no chronotropic effects on the heart at these doses.