CAS NO: | 352553-42-5 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
Cas No. | 352553-42-5 |
分子式 | C14H13NO2 |
分子量 | 227.26 |
溶解度 | DMSO : 100 mg/mL (440.02 mM; Need ultrasonic) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | MS7972 is a small molecule that blocks human p53 and CREB binding protein association. MS7972 can almost completely block this BRD interaction at 50 μM[1]. Addition of MS7972 to the CBP BRD results in emission at 445 nm and quenching of the CBP BRD due to resonance energy transfer[1]. [1]. Sachchidanand, et al. Target structure-based discovery of small molecules that block human p53 and CREB binding protein association. Chem Biol. 2006 Jan;13(1):81-90. |