(E)-Methyl 4-coumarate

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CAS NO:

19367-38-5

包装与价格：

包装	价格(元)
10mM (in 1mL DMSO)	电议
100mg	电议

产品介绍

(E)-Methyl4-coumarate(Methyl4-hydroxycinnamate)在几种植物中发现，如葱(Alliumcepa)或noni(MorindacitrifoliaL.)叶中。(E)-Methyl4-coumarate与CarnosicAcid联用可诱导细胞凋亡，杀死急性髓性白血病细胞，但不能杀死正常的外周血单核细胞。(E)-Methyl4-coumarate具有抗氧化和抗菌活性。

Cas No.	19367-38-5
别名	4-羟基肉桂酸甲酯; Methyl trans-p-coumarate
Canonical SMILES	O=C(OC)/C=C/C1=CC=C(O)C=C1.[E]
分子式	C₁₀H₁₀O₃
分子量	178.18
溶解度	DMSO: 100 mg/mL (561.23 mM)
储存条件	Store at -20℃
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	(E)-Methyl 4-coumarate (Methyl 4-hydroxycinnamate), found in several plants, such as green onion (Allium cepa) or noni (Morinda citrifolia L.) leaves. (E)-Methyl 4-coumarate cooperates with Carnosic Acid in inducing apoptosis and killing acute myeloid leukemia cells, but not normal peripheral blood mononuclear cells. Antioxidant and antimicrobial activity. [1]. Trachtenberg A, et al. Synergistic Cytotoxicity of Methyl 4-Hydroxycinnamate and Carnosic Acid to Acute Myeloid Leukemia Cells via Calcium-Dependent Apoptosis Induction. Front Pharmacol. 2019 May 9;10:507.