CAS NO: | 5813-86-5 |
包装 | 价格(元) |
5 g | 电议 |
10 g | 电议 |
25 g | 电议 |
Cas No. | 5813-86-5 |
别名 | 3-甲氧基苯甲酰胺,3-MBA |
Canonical SMILES | COC1=CC=CC(C(N)=O)=C1 |
分子式 | C8H9NO2 |
分子量 | 151.2 |
溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.50 mg/ml,Ethanol: 1 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | m-Methoxybenzamide is an inhibitor of poly(ADP-ribose) polymerase (PARP; Ki=<2 µm).1It also inhibits human placental ADP ribosyl transferase activity by 93% when used at a concentration of 100 µM.2m-Methoxybenzamide (100, 200, and 300 mg/kg) increases the pain threshold in the paw pinch test in rats.3 1.Purnell, M.R., and Whish, W.J.Novel inhibitors of poly(ADP-ribose) synthetaseBiochem. J.185(3)775-777(1980) 2.Burtscher, H.J., Auer, B., Klocker, H., et al.Isolation of ADP-ribosyltransferase by affinity chromatographyAnal. Biochem.152(2)285-290(1986) 3.Sanders, R., Dill, R.E., Dorris, R.L., et al.Analgesic effects of 3-methoxybenzamide in ratsJ. Pharm. Pharmacol.41(4)268-269(1989) |