您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > TC AC 28
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
TC AC 28
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
TC AC 28图片
CAS NO:1809296-92-1
包装:1mg
市场价:956元

产品介绍
Cas No.1809296-92-1
Canonical SMILESCOC(CC1N=C(C2=CC(OC)=CC=C2N3C(C)=NN=C13)C4=C5C=CNC5=CC=C4)=O
分子式C23H21N5O3
分子量415.44
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

High affinity BET bromodomain ligand (Kd values are 40 and 800 nM for Brd2(2) and Brd2(1), respectively). Exhibits 20-fold selectively for the second over the first bromodomain.

Baud et al (2016) New synthetic routes to triazolo-benzodiazepine analogues: expanding the scope of the bump-and-hole approach for selective bromo and extra-terminal (BET) bromodomain inhibition. J.Med.Chem. 59 1492 PMID:26367539