CAS NO: | 2084811-68-5 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
Cas No. | 2084811-68-5 |
Canonical SMILES | O=C(O)C1=CC=CC(S(=O)(NCCN2N=NC(CCNC(CCC(NC3=CC=CC(C(N)=O)=C3)=O)=O)=C2)=O)=C1 |
分子式 | C24H27N7O7S |
分子量 | 557.58 |
溶解度 | DMSO: 62.5 mg/mL (112.09 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis[1]. [1]. Peng B, et al. Small Molecule Microarray Based Discovery of PARP14 Inhibitors. Angew Chem Int Ed Engl. 2017 Jan 2;56(1):248-253. |