您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Tauroursodeoxycholic Acid(sodium salt hydrate)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Tauroursodeoxycholic Acid(sodium salt hydrate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tauroursodeoxycholic Acid(sodium salt hydrate)图片
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议

产品介绍
A taurine-conjugated form of ursodeoxycholic acid
Canonical SMILESC[C@H](CCC(NCCS([O-])(=O)=O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C.[Na+].O
分子式C26H44NO6S·Na [XH2O]
分子量521.7
溶解度DMF: 25 mg/ml,DMSO: 20 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7.2): 1 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Tauroursodeoxycholic acid (TUDCA) is a taurine-conjugated form of the secondary bile acid ursodeoxycholic acid .1,2TUDCA is found in small quantities in human bile but at a higher concentration in the bile of black bears.2It demonstrates anti-apoptotic activity in rodent models of tauopathy, Huntington’s disease, ischemic brain injury, and retinal disorders.3,2

1.Beuers, U.Effects of bile acids on hepatocellular signaling and secretionYale J. Biol. Med.70(4)341-346(1997) 2.Boatright, J.H., Nickerson, J.M., Moring, A.G., et al.Bile acids in treatment of ocular diseaseJ. Ocul. Biol. Dis. Infor.2(3)149-159(2009) 3.Vang, S., Longley, K., Steer, C.J., et al.The unexpected uses of urso- and tauroursodeoxycholic acid in the treatment of non-liver diseasesGlob. Adv. Health Med.3(3)58-69(2014)