| CAS NO: | 35045-72-8 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| Cas No. | 35045-72-8 |
| 别名 | L-缬氨酸-D8; L-VALINE-2,3,4,4,4,5,5,5-d8 |
| Canonical SMILES | [2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])[C@@](N)([2H])C(O)=O |
| 分子式 | C5H3D8NO2 |
| 分子量 | 125.2 |
| 溶解度 | PBS (pH 7.2): 1 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | L-Valine-d8is intended for use as an internal standard for the quantification of L-valine by GC- or LC-MS. L-Valine is a branched-chain essential amino acid that is obtainedviathe diet.1It is considered glucogenic due to its catabolism that ultimately forms succinyl-CoA, which enters the citric acid cycle.2A deficiency in branched-chain dehydrogenase, the enzyme that catabolizes valine, isoleucine, and leucine, leads to maple syrup urine disease, a disorder characterized by progressive ketoacidosis, failure to thrive, neurological dysfunction, and, potentially, death.1,3 1.Berg, J.M., Tymoczko, J.L., and Stryer, L.Biochemistry(2002) 2.Massey, K.A., Blakeslee, C.H., and Pitkow, H.S.A review of physiological and metabolic effects of essential amino acidsAmino Acids14(4)271-300(1998) 3.Farias, H.R., Gabriel, J.R., Cecconi, M.L., et al.The metabolic effect of α-ketoisocaproic acid: In vivo and in vitro studiesMetab. Brain Dis.36(1)185-192(2021) |
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